Gum resin from ancient plant drastically reduces painful, swollen joints in osteoarthritis and rheumatoid arthritis sufferers
In recent years, the gum resin extracted from the ancient plant, Frankincense (Boswellia Serrata), has gained considerable attention as a potent anti-inflammatory, anti-arthritic agent. It is highly effective in reducing inflammation, reducing pain, and preventing the loss of cartilage.
5-LOX & MMP-3 - The key enzymes initiating Osteoarthritis (OA) & Rheumatoid Arthritis (RA)
5-LOX is a member of the lipoxygenase family of enzymes that facilitates undesirable cell division changes. It plays a key role in the biosynthesis of pro-inflammatory compounds (leukotrienes) that mediate attacks on joints, arterial walls and other tissues. The typical modern diet rich in red meat, poultry, eggs and dairy products, increases the production of 5-LOX, hence worsening inflammation.
In addition, matrix metalloproteinase 3 (MMP-3) is an enzyme that breaks down proteins and peptides in the synovial tissues in response to inflammation, and thus causing cartilage destruction in OA and RA. In the extracellular space, MMP-3 triggers microglia to produce pro-inflammatory and cytotoxic molecules which further degrade cartilage matrix and other components of connective tissue in the joints.
TRUFLEX® significantly hampers 5-LOX & MMP-3
In particular, the 3-0-acetyl-11-keto-beta boswellic acid (AKBA) is the most active compound of Frankincense extract and is a potent inhibitor of 5-LOX and MMP-3 enzymes. Without the enzymes to trigger the release of pro-inflammatory chemicals, pain and inflammation are prevented or reduced.
A great improvement in inflammation provides better flexibility and joint motion. In addition, by inhibiting the breakdown of connective tissue, joint degeneration is slowed, and the body is given time to heal itself.
TRUFLEX® employs a patented enrichment process, selecting only the most active AKBA and blending it with the know-how Boswellia serrata non-volatile oil extract.
This patented synergistic composition results in at least 20% of bioactive AKBA for direct absorption, making TRUFLEX® more efficacious for overall joint health than any other existing Frankincense extract available in the market.
Of late, this has earned TRUFLEX® the recognition and honour of winning the 2019 Readers' Choice Award for BEST JOINT RELIEF SUPPLEMENT.